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Migraine with aura

DOID EFO Endpoint Browser PheWeb

G6_MIGRAINE_WITH_AURA

migraine with aura: A migraine disorder characterized by episodes that are preceded by focal neurological symptoms.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G43.1#
  • Hospital discharge: ICD-9 — 3460
  • Cause of death: ICD-10 — G43.1#
  • Cause of death: ICD-9 — 3460

2 out of 7 registries used, show all original rules.

9272

4. Check minimum number of events

None

9272

5. Include endpoints

None

9272

6. Filter based on genotype QC (FinnGen only)

8970

Control definitions (FinnGen only)

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 G43
Name in latin Hemicrania cum aura

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 70820 53638 16847
Only index persons 69217 52835 16382
Unadjusted period prevalence (%)
Whole population 1.28 1.54 0.47
Only index persons 1.63 1.94 0.63
Median age at first event (years)
Whole population 35.29 35.91 33.30
Only index persons 35.42 35.96 33.66

-FinnGen-

Key figures

All Female Male
Number of individuals 8970 7455 1515
Unadjusted period prevalence (%) 2.83 3.24 0.83
Median age at first event (years) 42.09 40.90 47.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_MIGRAINE_WITH_AURA – Migraine with aura

GWS hits: 2

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