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Migraine without aura

DOID EFO Endpoint Browser PheWeb

G6_MIGRAINE_NO_AURA

migraine without aura: A migraine disorder characterized by episodes that occur in the absence of preceding focal neurological symptoms.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G43.0#
  • Hospital discharge: ICD-9 — 3461
  • Cause of death: ICD-10 — G43.0#
  • Cause of death: ICD-9 — 3461

2 out of 7 registries used, show all original rules.

7907

4. Check minimum number of events

None

7907

5. Include endpoints

None

7907

6. Filter based on genotype QC (FinnGen only)

7593

Control definitions (FinnGen only)

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 G43
Name in latin Hemicrania sine aura

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 65091 46781 17966
Only index persons 62132 45519 16613
Unadjusted period prevalence (%)
Whole population 1.10 1.34 0.50
Only index persons 1.40 1.67 0.63
Median age at first event (years)
Whole population 28.61 32.80 17.56
Only index persons 29.50 33.13 19.57

-FinnGen-

Key figures

All Female Male
Number of individuals 7593 6485 1108
Unadjusted period prevalence (%) 2.49 2.82 0.61
Median age at first event (years) 38.10 37.95 39.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: G6_MIGRAINE_NO_AURA – Migraine without aura

GWS hits: 4

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