Enduring personality changes

F5_PERSOCHANGE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F62
  • Cause of death: ICD-10 F62

2 out of 7 registries used, show all original rules.

130

4. Check minimum number of events

None

130

5. Include endpoints

None

130

6. Filter based on genotype QC (FinnGen only)

124

Control definitions (FinnGen only)

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F60-F62
Name in latin Commutationes personalitatis persistentes non laesioni neque morbo cerebri ascribendae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1229 593 625
Only index persons 1114 557 557
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 43.28 42.70 43.81
Only index persons 42.94 42.65 43.22

-FinnGen-

Key figures

All Female Male
Number of individuals 124 71 53
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 45.21 42.45 48.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: F5_PERSOCHANGE – Enduring personality changes

GWS hits: -

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