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Gender identity disorders

DOID EFO Endpoint Browser PheWeb

F5_GENDER

gender identity disorder: A disorder characterized by a strong and persistent cross-gender identification (such as stating a desire to be the other sex or frequently passing as the other sex) coupled with persistent discomfort with his or her sex (manifested in adults, for example, as a preoccupation with altering primary and secondary sex characteristics through hormonal manipulation or surgery).

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F64
  • Hospital discharge: ICD-9 — 3023|302[5-6]
  • Hospital discharge: ICD-8 — 3023
  • Cause of death: ICD-10 — F64
  • Cause of death: ICD-9 — 3023|302[5-6]
  • Cause of death: ICD-8 — 3023

2 out of 7 registries used, show all original rules.

382

4. Check minimum number of events

None

382

5. Include endpoints

None

382

6. Filter based on genotype QC (FinnGen only)

366

Control definitions (FinnGen only)

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F63-F69
Name in latin Perturbationes identitatis generis

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5826 3422 2338
Only index persons 5682 3391 2291
Unadjusted period prevalence (%)
Whole population 0.08 0.10 0.07
Only index persons 0.11 0.12 0.09
Median age at first event (years)
Whole population 22.20 20.84 23.99
Only index persons 22.03 20.81 23.84

-FinnGen-

Key figures

All Female Male
Number of individuals 366 244 122
Unadjusted period prevalence (%) 0.09 0.11 0.07
Median age at first event (years) 26.42 23.75 31.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: F5_GENDER – Gender identity disorders

GWS hits: -

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