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Subacute thyroiditis

DOID EFO Endpoint Browser PheWeb

E4_THYROIDITSUBAC

subacute thyroiditis: Spontaneously remitting inflammatory condition of the THYROID GLAND, characterized by FEVER; MUSCLE WEAKNESS; SORE THROAT; severe thyroid PAIN; and an enlarged damaged gland containing GIANT CELLS. The disease frequently follows a viral infection.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — E06.1
  • Hospital discharge: ICD-10 — E06.1
  • Hospital discharge: ICD-9 — 2451
  • Hospital discharge: ICD-8 — 2450[0-1]
  • Cause of death: ICD-10 — E06.1
  • Cause of death: ICD-9 — 2451
  • Cause of death: ICD-8 — 2450[0-1]

3 out of 7 registries used, show all original rules.

1085

4. Check minimum number of events

None

1085

5. Include endpoints

None

1085

6. Filter based on genotype QC (FinnGen only)

1050

Control definitions (FinnGen only)

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF10
Parent code in ICD-10 E06
Name in latin Thyreoiditis subacuta

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8817 6740 2008
Only index persons 8221 6380 1841
Unadjusted period prevalence (%)
Whole population 0.16 0.19 0.06
Only index persons 0.20 0.23 0.07
Median age at first event (years)
Whole population 48.24 47.71 50.24
Only index persons 47.78 47.28 49.55

-FinnGen-

Key figures

All Female Male
Number of individuals 1050 868 182
Unadjusted period prevalence (%) 0.33 0.38 0.10
Median age at first event (years) 47.75 47.47 49.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: E4_THYROIDITSUBAC – Subacute thyroiditis

GWS hits: 5

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