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Testicular hypofunction

DOID EFO Endpoint Browser PheWeb

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only males

189303

2. Check conditions

None

189303

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E29.1#
  • Hospital discharge: ICD-9 — 257[1-2]
  • Hospital discharge: ICD-8 — 2571
  • Cause of death: ICD-10 — E29.1#
  • Cause of death: ICD-9 — 257[1-2]
  • Cause of death: ICD-8 — 2571
  • KELA reimbursements: KELA codes — ANY
  • KELA reimbursements: ICD-10 — E29.1#

3 out of 7 registries used, show all original rules.

810

4. Check minimum number of events

None

810

5. Include endpoints

None

810

6. Filter based on genotype QC (FinnGen only)

782

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E29
Name in latin Hypofunctio testium

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4793 - 4793
Only index persons 4698 - 4698
Unadjusted period prevalence (%)
Whole population 0.13 - 0.13
Only index persons 0.18 - 0.18
Median age at first event (years)
Whole population - - 48.75
Only index persons - - 48.71

-FinnGen-

Key figures

All Female Male
Number of individuals 782 - 782
Unadjusted period prevalence (%) 0.43 - 0.43
Median age at first event (years) 51.21 - 51.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: E4_TESTICHYPO – Testicular hypofunction

GWS hits: -

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