nodular goiter: Goiter characterized by discrete tissue mass(es) that may or may not produce thyroid hormones.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2288 |
4. Check minimum number of eventsNone |
2288 |
5. Include endpointsNone |
2288 |
6. Filter based on genotype QC (FinnGen only) |
2203 |
Control definitions (FinnGen only)
Control exclude
E4_THYROID
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E04
Name in latin
Struma atoxica uninodularis
Similar endpoints
↥List of similar endpoints to
Nontoxic single thyroid nodule
based on the number of shared cases.
Broader endpoints:
- Nontoxic goitre/thyroid nodule
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17821 | 14391 | 3351 |
| Only index persons | 16839 | 13735 | 3104 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.35 | 0.41 | 0.09 |
| Only index persons | 0.43 | 0.50 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 51.50 | 50.54 | 55.53 |
| Only index persons | 50.93 | 50.05 | 54.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2203 | 1783 | 420 |
| Unadjusted period prevalence (%) | 0.67 | 0.77 | 0.23 |
| Median age at first event (years) | 51.36 | 49.51 | 59.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_GOITRENOD – Nontoxic single thyroid nodule
GWS hits: 2
Loading Relationships table