No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditions
|
71320 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
3057 |
6. Filter based on genotype QC (FinnGen only) |
2959 |
Control definitions (FinnGen only)
Control conditions
not I9_IHD
Extra metadata
Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF6v3
Similar endpoints
↥List of similar endpoints to
Familial hypercholesterolemia, with ischemic heart disease
based on the number of shared cases.
Broader endpoints:
- Familial hypercholesterolemia
- Pure hypercholesterolaemia
- Disorders of lipoprotein metabolism and other lipidaemias
- Metabolic disorders
- Ischaemic heart disease, wide definition
Narrower endpoints:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26704 | 11042 | 15581 |
| Only index persons | 25221 | 10477 | 14744 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.39 | 0.32 | 0.44 |
| Only index persons | 0.49 | 0.39 | 0.56 |
| Median age at first event (years) | |||
| Whole population | 70.10 | 74.13 | 67.25 |
| Only index persons | 70.07 | 74.09 | 67.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2959 | 960 | 1999 |
| Unadjusted period prevalence (%) | 0.88 | 0.42 | 1.10 |
| Median age at first event (years) | 66.57 | 67.63 | 66.07 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: E4_FH_IHD – Familial hypercholesterolemia, with ischemic heart disease
GWS hits: 14
Loading Relationships table