Other adrenocortical overactivity

E4_ADREACT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E27.0
  • Hospital discharge: ICD-9 2553A
  • Hospital discharge: ICD-8 25508
  • Cause of death: ICD-10 E27.0
  • Cause of death: ICD-9 2553A
  • Cause of death: ICD-8 25508

2 out of 7 registries used, show all original rules.

173

4. Check minimum number of events

None

173

5. Include endpoints

None

173

6. Filter based on genotype QC (FinnGen only)

165

Control definitions (FinnGen only)

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E27
Name in latin Alia hyperfunctio adrenocorticalis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4574 3566 1002
Only index persons 3335 2615 720
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.03
Only index persons 0.08 0.10 0.03
Median age at first event (years)
Whole population 7.91 7.69 8.52
Only index persons 8.08 7.85 8.90

-FinnGen-

Key figures

All Female Male
Number of individuals 165 134 31
Unadjusted period prevalence (%) 0.05 0.06 0.02
Median age at first event (years) 15.72 8.82 45.58

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: E4_ADREACT – Other adrenocortical overactivity

GWS hits: -

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