autoimmune thrombocytopenic purpura: An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
912 |
4. Check minimum number of eventsNone |
912 |
5. Include endpointsNone |
912 |
6. Filter based on genotype QC (FinnGen only) |
882 |
Control definitions (FinnGen only)
Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D69
Name in latin
Purpura idiopathica thrombocytopenica
Similar endpoints
↥List of similar endpoints to
Idiopathic thrombocytopenic purpura
based on the number of shared cases.
Broader endpoints:
- Purpura and other haemorrhagic conditions
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9562 | 4823 | 4657 |
| Only index persons | 8094 | 4155 | 3939 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.14 | 0.13 |
| Only index persons | 0.15 | 0.15 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 50.61 | 48.79 | 52.21 |
| Only index persons | 47.50 | 45.05 | 50.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 882 | 461 | 421 |
| Unadjusted period prevalence (%) | 0.22 | 0.20 | 0.23 |
| Median age at first event (years) | 49.96 | 40.60 | 60.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: D3_ITP – Idiopathic thrombocytopenic purpura
GWS hits: 1
Loading Relationships table