Selective deficiency of immunoglobulin G [IgG] subclasses

D3_DEF_IGG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D80.3
  • Cause of death: ICD-10 D80.3

2 out of 7 registries used, show all original rules.

208

4. Check minimum number of events

None

208

5. Include endpoints

None

208

6. Filter based on genotype QC (FinnGen only)

200

Control definitions (FinnGen only)

Control exclude D3_IMMUNEMECHANISM

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D80
Name in latin Deficientia selectiva subclassium immunoglobulini G

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1014 665 344
Only index persons 956 637 319
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.01
Median age at first event (years)
Whole population 43.56 45.95 38.66
Only index persons 44.64 46.75 40.42

-FinnGen-

Key figures

All Female Male
Number of individuals 200 148 52
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 48.00 47.95 48.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: D3_DEF_IGG – Selective deficiency of immunoglobulin G [IgG] subclasses

GWS hits: -

loading spinner Loading Relationships table