blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1422 |
4. Check minimum number of eventsNone |
1422 |
5. Include endpointsNone |
1422 |
6. Filter based on genotype QC (FinnGen only) |
1375 |
Control definitions (FinnGen only)
Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified coagulation defects
based on the number of shared cases.
Broader endpoints:
- Other coagulation defects
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Narrower endpoints:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11374 | 7399 | 3902 |
| Only index persons | 10454 | 6997 | 3457 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.21 | 0.11 |
| Only index persons | 0.22 | 0.26 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 41.80 | 37.06 | 50.90 |
| Only index persons | 41.92 | 37.10 | 51.69 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1375 | 975 | 400 |
| Unadjusted period prevalence (%) | 0.36 | 0.42 | 0.22 |
| Median age at first event (years) | 45.46 | 41.04 | 56.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: D3_COAGDEFNAS – Other and unspecified coagulation defects
GWS hits: 28
Loading Relationships table