Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
972 |
4. Check minimum number of eventsNone |
972 |
5. Include endpointsNone |
972 |
6. Filter based on genotype QC (FinnGen only) |
939 |
Control definitions (FinnGen only)
Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D69
Name in latin
Purpura allergica
Similar endpoints
↥List of similar endpoints to
Allergic purpura
based on the number of shared cases.
Broader endpoints:
- Purpura and other haemorrhagic conditions
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11658 | 5675 | 5938 |
| Only index persons | 10225 | 5070 | 5155 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.16 | 0.17 |
| Only index persons | 0.19 | 0.19 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 19.15 | 23.45 | 14.73 |
| Only index persons | 18.96 | 23.33 | 14.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 939 | 556 | 383 |
| Unadjusted period prevalence (%) | 0.23 | 0.24 | 0.21 |
| Median age at first event (years) | 39.86 | 34.31 | 47.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: D3_ALLERGPURPURA – Allergic purpura
GWS hits: 2
Loading Relationships table