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Drug-induced autoimmune haemolytic anaemia

DOID EFO Endpoint Browser

D3_AIHA_DRUG

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D59.0#
  • Hospital discharge: ICD-9 — 2830B
  • Hospital discharge: ICD-8 — 28391
  • Cause of death: ICD-10 — D59.0#
  • Cause of death: ICD-9 — 2830B
  • Cause of death: ICD-8 — 28391

2 out of 7 registries used, show all original rules.

40

4. Check minimum number of events

None

40

5. Include endpoints

None

40

6. Filter based on genotype QC (FinnGen only)

39

Control definitions (FinnGen only)

Control exclude D3_HAEMOLYTICANAEMIA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D59
Name in latin Anaemia autoimmunis haemolytica medicamentis provocata

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 547 318 222
Only index persons 353 208 145
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 61.21 62.60 59.20
Only index persons 53.14 57.03 47.57

-FinnGen-

Key figures

All Female Male
Number of individuals 39 22 17
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 58.34 57.22 59.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: D3_AIHA_DRUG – Drug-induced autoimmune haemolytic anaemia

GWS hits: -

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