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Chronic drug-induced interstitial lung disorders

CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J70.3#

1 out of 7 registries used, show all original rules.

46

4. Check minimum number of events

None

46

5. Include endpoints

None

46

6. Filter based on genotype QC (FinnGen only)

46

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 444 290 152
Only index persons 328 215 113
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 73.02 75.38 68.75
Only index persons 71.67 74.75 65.82

-FinnGen-

Key figures

All Female Male
Number of individuals 46 25 21
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 63.54 61.63 65.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CHRONIC_DRUGADVERS_INTERSTITIAL_LUNG_DISORD – Chronic drug-induced interstitial lung disorders

GWS hits: -

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