Acute drug-induced interstitial lung disorder

ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J70.2#

1 out of 7 registries used, show all original rules.

210

4. Check minimum number of events

None

210

5. Include endpoints

None

210

6. Filter based on genotype QC (FinnGen only)

205

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2095 1174 893
Only index persons 1591 915 676
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.02
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 71.85 72.84 70.45
Only index persons 70.45 71.25 69.35

-FinnGen-

Key figures

All Female Male
Number of individuals 205 96 109
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 67.42 63.13 71.19

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ACUTE_DRUGADVERS_INTERSTITIAL_LUNG_DISORD – Acute drug-induced interstitial lung disorder

GWS hits: -

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