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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Biliary cirrhosis, secondary

CHIRBIL_SEC

cirrhosis of liver: A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K74.4
  • Cause of death: ICD-10 K74.4

2 out of 7 registries used, show all original rules.

22

4. Check minimum number of events

None

22

5. Include endpoints

None

22

6. Filter based on genotype QC (FinnGen only)

22

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K74
Name in latin Cirrhosis biliaris secundaria

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 213 111 99
Only index persons 148 84 64
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 60.31 62.10 58.46
Only index persons 59.37 60.04 58.50

-FinnGen-

Key figures

All Female Male
Number of individuals 22 16 6
Unadjusted period prevalence (%) 0.01 0.01 0.00
Median age at first event (years) 57.63 57.17 58.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: CHIRBIL_SEC – Biliary cirrhosis, secondary

GWS hits: -

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