Malignant neoplasm of prostate (controls excluding all cancers)

C3_PROSTATE_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

only males

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C61
  • Cause of death: ICD-9 185
  • Cause of death: ICD-8 185
  • KELA reimbursements: KELA codes 116
  • Cancer registry: Topography ICD-O-3 C61
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 127018 - 127018
Only index persons 94971 - 94971
Unadjusted period prevalence (%)
Whole population 3.55 - 3.55
Only index persons 3.63 - 3.63
Median age at first event (years)
Whole population - - 70.94
Only index persons - - 70.00

-FinnGen-

Key figures

All Female Male
Number of individuals 15199 - 15199
Unadjusted period prevalence (%) 8.36 - 8.36
Median age at first event (years) 69.26 - 69.26

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_PROSTATE_EXALLC – Malignant neoplasm of prostate (controls excluding all cancers)

GWS hits: 88

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