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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_OESOPHAGUS_EXALLC for full statistics.

Malignant neoplasm of oesophagus


esophageal squamous cell carcinoma: Esophageal squamous cell carcinoma (ESCC) is a type of esophageal carcinoma (EC; see this term) that can affect any part of the esophagus, but is usually located in the upper or middle third.

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Endpoint definition

Endpoint definition steps


Phenotype data


1. Apply sex-specific rule



2. Check conditions



3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C15
  • Cause of death: ICD-9 150
  • Cause of death: ICD-8 150
  • Cancer registry: Topography ICD-O-3 C15
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.


4. Check minimum number of events



5. Include endpoints



6. Filter based on genotype QC (FinnGen only)


Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics


This endpoint is excluded from FinRegistry analyses (omitted endpoint).


Key figures

All Female Male
Number of individuals 619 130 489
Unadjusted period prevalence (%) 0.22 0.06 0.27
Median age at first event (years) 69.58 70.03 69.46


Age distribution of first events


Year distribution of first events


Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_OESOPHAGUS – Malignant neoplasm of oesophagus

GWS hits: -

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