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Malignant melanoma of skin (controls excluding all cancers)

Endpoint Browser PheWeb

C3_MELANOMA_SKIN_EXALLC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C43
  • Cause of death: ICD-9 — 172
  • Cause of death: ICD-8 — 172
  • Cancer registry: Topography ICD-O-3 — C44
  • Cancer registry: Morphology ICD-O-3 — 8720|8721|8726|8730|8742|8743|8744|8745
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

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FinnGen case counts by registry codes:

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Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 34815 16705 17718
Only index persons 27945 14077 13868
Unadjusted period prevalence (%)
Whole population 0.49 0.48 0.50
Only index persons 0.52 0.52 0.53
Median age at first event (years)
Whole population 61.69 60.06 63.21
Only index persons 61.38 59.26 63.54

-FinnGen-

Key figures

All Female Male
Number of individuals 3194 1542 1652
Unadjusted period prevalence (%) 0.79 0.67 0.91
Median age at first event (years) 60.77 56.77 64.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: C3_MELANOMA_SKIN_EXALLC – Malignant melanoma of skin (controls excluding all cancers)

GWS hits: 11

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