Malignant melanoma (controls excluding all cancers)

C3_MELANOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

4 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 43044 21308 21302
Only index persons 35457 18316 17141
Unadjusted period prevalence (%)
Whole population 0.60 0.61 0.60
Only index persons 0.66 0.67 0.65
Median age at first event (years)
Whole population 63.08 61.97 64.19
Only index persons 62.92 61.47 64.47

-FinnGen-

Key figures

All Female Male
Number of individuals 4261 2092 2169
Unadjusted period prevalence (%) 1.05 0.91 1.19
Median age at first event (years) 62.71 59.47 65.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_MELANOMA_EXALLC – Malignant melanoma (controls excluding all cancers)

GWS hits: 12

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