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Non-small cell lung cancer (controls excluding all cancers)

Endpoint Browser PheWeb

C3_LUNG_NONSMALL_EXALLC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

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2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — C34.[123457]
  • Cause of death: ICD-10 — C34.[123457]
  • Cancer registry: Topography ICD-O-3 — C34
  • Cancer registry: Morphology ICD-O-3 — 8046|8070|8140
  • Cancer registry: Behaviour codes — 3

3 out of 7 registries used, show all original rules.

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4. Check minimum number of events

None

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5. Include endpoints

None

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6. Filter based on genotype QC (FinnGen only)

None

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Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF9

Similar endpoints

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List of similar endpoints to Non-small cell lung cancer (controls excluding all cancers) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

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Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 55170 14551 38739
Only index persons 26307 9690 16617
Unadjusted period prevalence (%)
Whole population 0.94 0.42 1.08
Only index persons 0.53 0.36 0.63
Median age at first event (years)
Whole population 68.26 68.97 68.07
Only index persons 70.15 69.88 70.30

-FinnGen-

Key figures

All Female Male
Number of individuals 5315 1465 3850
Unadjusted period prevalence (%) 1.71 0.64 2.12
Median age at first event (years) 71.03 68.42 72.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: C3_LUNG_NONSMALL_EXALLC – Non-small cell lung cancer (controls excluding all cancers)

GWS hits: 5

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