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Malignant neoplasm of liver and intrahepatic bile ducts

DOID Endpoint Browser

C3_LIVER_INTRAHEPATIC_BILE_DUCTS

liver neoplasm: A benign or malignant epithelial neoplasm that affects the liver parenchyma and intrahepatic bile ducts. Representative examples of benign epithelial neoplasms include hepatocellular adenoma and intrahepatic bile duct adenoma. Representative examples of malignant epithelial neoplasms include hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C22
  • Cause of death: ICD-9 — 155
  • Cause of death: ICD-8 — 155
  • Cancer registry: Topography ICD-O-3 — C22
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

881

4. Check minimum number of events

None

881

5. Include endpoints

None

881

6. Filter based on genotype QC (FinnGen only)

845

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF9

Similar endpoints

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List of similar endpoints to Malignant neoplasm of liver and intrahepatic bile ducts based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 845 157 688
Unadjusted period prevalence (%) 0.32 0.07 0.38
Median age at first event (years) 72.41 71.21 72.68

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_LIVER_INTRAHEPATIC_BILE_DUCTS – Malignant neoplasm of liver and intrahepatic bile ducts

GWS hits: -

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