Malignant neoplasm of lip (controls excluding all cancers)

C3_LIP_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C00&
  • Cause of death: ICD-9 140
  • Cause of death: ICD-8 140
  • Cancer registry: Topography ICD-O-3 C00
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

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Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5123 1032 3949
Only index persons 2162 666 1496
Unadjusted period prevalence (%)
Whole population 0.10 0.03 0.11
Only index persons 0.05 0.02 0.06
Median age at first event (years)
Whole population 67.63 75.25 65.76
Only index persons 69.86 75.01 67.57

-FinnGen-

Key figures

All Female Male
Number of individuals 219 45 174
Unadjusted period prevalence (%) 0.08 0.02 0.10
Median age at first event (years) 66.83 71.14 65.72

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_LIP_EXALLC – Malignant neoplasm of lip (controls excluding all cancers)

GWS hits: 2

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