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Malignant neoplasm of heart, mediastinum and pleura

DOID Endpoint Browser

C3_HEART_MEDIASTINUM_PLEURA

Heart neoplasm: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C38
  • Cause of death: ICD-9 — 16[3-4]
  • Cause of death: ICD-8 — 163[0-1]
  • Cause of death: excluded ICD-9 — 1640
  • Cancer registry: Topography ICD-O-3 — C38
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

308

4. Check minimum number of events

None

308

5. Include endpoints

None

308

6. Filter based on genotype QC (FinnGen only)

300

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Similar endpoints

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List of similar endpoints to Malignant neoplasm of heart, mediastinum and pleura based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 300 72 228
Unadjusted period prevalence (%) 0.10 0.03 0.13
Median age at first event (years) 69.22 62.48 71.34

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: C3_HEART_MEDIASTINUM_PLEURA – Malignant neoplasm of heart, mediastinum and pleura

GWS hits: -

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