Fibrosarcoma (controls excluding all cancers)

C3_FIBROSARCOMA_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C47.5|C48.5|C49.5
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 8810|8811|8814|8815|8821|8830|8832|8840
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze DF8

Case counts by codes

FinnGen case counts by registry codes:

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No upset table: script not run.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2775 1326 1389
Only index persons 1685 856 829
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 54.62 54.26 54.68
Only index persons 49.38 49.77 48.97

-FinnGen-

Key figures

All Female Male
Number of individuals 191 86 105
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 50.87 49.98 51.59

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: C3_FIBROSARCOMA_EXALLC – Fibrosarcoma (controls excluding all cancers)

GWS hits: 1

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