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Malignant neoplasm of breast, HER-negative

C3_BREAST_ERNEG

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

  • not RX_ERPLUS
227572

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C50
  • Cause of death: ICD-9 174
  • Cause of death: ICD-8 174
  • Cancer registry: Topography ICD-O-3 C50
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes [23]

2 out of 7 registries used, show all original rules.

6414

4. Check minimum number of events

None

6414

5. Include endpoints

None

6414

6. Filter based on genotype QC (FinnGen only)

6188

Control definitions (FinnGen only)

Control conditions not RX_ERPLUS

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 6188 6188 -
Unadjusted period prevalence (%) 2.69 2.69 -
Median age at first event (years) 57.70 57.70 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_BREAST_ERNEG – Malignant neoplasm of breast, HER-negative

GWS hits: -

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