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Viral infections characterized by skin and mucous membrane lesions

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AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

rubella: A viral infectious disease that results_in infection located_in skin, has_material_basis_in Rubella virus, which is transmitted_by droplet spread of oronasal secretions from the infected person through coughing and sneezing, and transmitted_by congenital method. The infection has_symptom rash on the face which spreads to the trunk and limbs, has_symptom fever, has_symptom lymphadenopathy, has_symptom joint pains, has_symptom headache, and has_symptom conjunctivitis. [ url:http://en.wikipedia.org/wiki/Rubella ]

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B00-B09
  • Hospital discharge: ICD-9 — 078[0-4]
  • Hospital discharge: ICD-8 — 079[0-1]
  • Hospital discharge: excluded ICD-9 — 0781C|0785|078[7-8]
  • Cause of death: ICD-10 — B00-B09
  • Cause of death: ICD-9 — 078[0-4]
  • Cause of death: ICD-8 — 079[0-1]
  • Cause of death: excluded ICD-9 — 0781C|0785|078[7-8]

2 out of 7 registries used, show all original rules.

12868

4. Check minimum number of events

None

12868

5. Include endpoints

16366

6. Filter based on genotype QC (FinnGen only)

15803

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 191273 94937 95357
Only index persons 160628 80030 80598
Unadjusted period prevalence (%)
Whole population 2.68 2.72 2.66
Only index persons 3.01 2.94 3.08
Median age at first event (years)
Whole population 31.40 41.93 20.66
Only index persons 31.83 42.87 20.87

-FinnGen-

Key figures

All Female Male
Number of individuals 15803 8685 7118
Unadjusted period prevalence (%) 3.84 3.77 3.91
Median age at first event (years) 45.05 47.45 42.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: AB1_VIRAL_SKIN_MUCOUS_MEMBRANE – Viral infections characterized by skin and mucous membrane lesions

GWS hits: 1

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