Atypical virus infections of central nervous system

AB1_ATYPICAL_CNS_VIRUS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A81
  • Hospital discharge: ICD-8 04[5-]
  • Cause of death: ICD-10 A81
  • Cause of death: ICD-8 04[5-]

2 out of 7 registries used, show all original rules.

291

4. Check minimum number of events

None

291

5. Include endpoints

None

291

6. Filter based on genotype QC (FinnGen only)

282

Control definitions (FinnGen only)

Control exclude AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2894 1340 1530
Only index persons 2514 1171 1343
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.05 0.04 0.05
Median age at first event (years)
Whole population 23.36 28.47 18.42
Only index persons 20.77 26.75 15.55

-FinnGen-

Key figures

All Female Male
Number of individuals 282 169 113
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 25.98 26.08 25.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: AB1_ATYPICAL_CNS_VIRUS – Atypical virus infections of central nervous system

GWS hits: 2

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