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Drugs, medicaments and biological substances causing adverse effects in therapeutic use

Endpoint Browser

VWXY20_DRUGS_MEDICAM_BIOLO_SUBST_CAUSI_ADVER_EFFEC_THERAPE_USE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Y40-Y59
  • Cause of death: ICD-10 — Y40-Y59

2 out of 7 registries used, show all original rules.

2827

4. Check minimum number of events

None

2827

5. Include endpoints

None

2827

6. Filter based on genotype QC (FinnGen only)

2718

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 Y40-Y84

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2718 1728 990
Unadjusted period prevalence (%) 0.68 0.75 0.54
Median age at first event (years) 58.92 56.19 63.70

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: VWXY20_DRUGS_MEDICAM_BIOLO_SUBST_CAUSI_ADVER_EFFEC_THERAPE_USE – Drugs, medicaments and biological substances causing adverse effects in therapeutic use

GWS hits: -

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