Fracture of lower leg, including ankle

ST19_FRACT_LOWER_LEG_INCLU_ANKLE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S82
  • Cause of death: ICD-10 S82

2 out of 7 registries used, show all original rules.

22744

4. Check minimum number of events

None

22744

5. Include endpoints

None

22744

6. Filter based on genotype QC (FinnGen only)

22027

Control definitions (FinnGen only)

Control exclude ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 S8
Name in latin Fractura genus/cruris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 289332 144128 144076
Only index persons 267282 134001 133281
Unadjusted period prevalence (%)
Whole population 4.07 4.13 4.03
Only index persons 5.01 4.93 5.09
Median age at first event (years)
Whole population 48.02 55.36 40.64
Only index persons 47.58 55.08 40.03

-FinnGen-

Key figures

All Female Male
Number of individuals 22027 12700 9327
Unadjusted period prevalence (%) 5.35 5.52 5.13
Median age at first event (years) 52.70 54.22 50.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: ST19_FRACT_LOWER_LEG_INCLU_ANKLE – Fracture of lower leg, including ankle

GWS hits: 5

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