Use of hypnotics and sedatives

RX_N05C

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N05C

1 out of 7 registries used, show all original rules.

74475

4. Check minimum number of events

Min. number of events 3
74475

5. Include endpoints

None

74475

6. Filter based on genotype QC (FinnGen only)

71952

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Similar endpoints

List of similar endpoints to Use of hypnotics and sedatives based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 791068 467501 316347
Only index persons 649689 398173 251516
Unadjusted period prevalence (%)
Whole population 11.52 13.39 8.84
Only index persons 12.69 14.64 9.60
Median age at first event (years)
Whole population 57.02 58.33 54.85
Only index persons 54.22 55.71 51.85

-FinnGen-

Key figures

All Female Male
Number of individuals 71952 42278 29674
Unadjusted period prevalence (%) 17.52 18.36 16.32
Median age at first event (years) 52.42 50.12 55.69

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RX_N05C – Use of hypnotics and sedatives

GWS hits: 33

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