No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
90340 |
4. Check minimum number of events
Min. number of events
3
|
90340 |
5. Include endpointsNone |
90340 |
6. Filter based on genotype QC (FinnGen only) |
87508 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF5
First line medication for Crohn's disease
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 696216 | 397475 | 293994 |
| Only index persons | 620665 | 362085 | 258580 |
| Unadjusted period prevalence (%) | |||
| Whole population | 10.00 | 11.38 | 8.21 |
| Only index persons | 11.88 | 13.31 | 9.87 |
| Median age at first event (years) | |||
| Whole population | 55.02 | 54.12 | 56.08 |
| Only index persons | 53.29 | 52.63 | 54.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 87508 | 51133 | 36375 |
| Unadjusted period prevalence (%) | 21.29 | 22.21 | 20.01 |
| Median age at first event (years) | 52.04 | 48.19 | 57.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: RX_CROHN_1STLINE – First line medication for Crohn's disease
GWS hits: 40
Loading Relationships table