Codeine or tramadol medication

RX_CODEINE_TRAMADOL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

1 out of 7 registries used, show all original rules.

68924

4. Check minimum number of events

Min. number of events 3
68924

5. Include endpoints

None

68924

6. Filter based on genotype QC (FinnGen only)

66771

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 536929 289248 246261
Only index persons 532577 287817 244760
Unadjusted period prevalence (%)
Whole population 7.62 8.28 6.88
Only index persons 10.01 10.58 9.34
Median age at first event (years)
Whole population 54.60 55.99 53.07
Only index persons 54.61 55.95 53.03

-FinnGen-

Key figures

All Female Male
Number of individuals 66771 38776 27995
Unadjusted period prevalence (%) 16.23 16.84 15.40
Median age at first event (years) 54.99 53.10 57.60

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication

GWS hits: 9

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