Biological medicines for asthma

RX_ASTMA_BIOL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC R03DX05|R03DX08|R03DX09|R03DX10|D11AH05

1 out of 7 registries used, show all original rules.

304

4. Check minimum number of events

Min. number of events 3
304

5. Include endpoints

None

304

6. Filter based on genotype QC (FinnGen only)

293

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1297 753 538
Only index persons 1280 749 531
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.02 0.03 0.02
Median age at first event (years)
Whole population 50.20 49.28 51.58
Only index persons 50.32 49.31 51.75

-FinnGen-

Key figures

All Female Male
Number of individuals 293 177 116
Unadjusted period prevalence (%) 0.07 0.08 0.06
Median age at first event (years) 55.82 55.80 55.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: RX_ASTMA_BIOL – Biological medicines for asthma

GWS hits: -

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