Congenital malformations of ear causing impairment of hearing

Q17_CONGEN_MALFO_EAR_CAUSI_IMPAIRM_HEARING

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q16
  • Cause of death: ICD-10 Q16

2 out of 7 registries used, show all original rules.

111

4. Check minimum number of events

None

111

5. Include endpoints

None

111

6. Filter based on genotype QC (FinnGen only)

109

Control definitions (FinnGen only)

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 Q1
Name in latin Malformationes congenitae auris cum hypacusi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1650 742 906
Only index persons 1416 646 770
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.03
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 11.63 13.91 9.73
Only index persons 14.11 16.09 12.45

-FinnGen-

Key figures

All Female Male
Number of individuals 109 64 45
Unadjusted period prevalence (%) 0.03 0.03 0.02
Median age at first event (years) 23.67 19.36 29.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: Q17_CONGEN_MALFO_EAR_CAUSI_IMPAIRM_HEARING – Congenital malformations of ear causing impairment of hearing

GWS hits: -

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