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Pneumococcal septicemia

DOID EFO Endpoint Browser PheWeb

PNEUMO_SEPTHICHE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A40.3
  • Hospital discharge: ICD-9 — 0382
  • Hospital discharge: ICD-8 — 0382
  • Cause of death: ICD-10 — A40.3
  • Cause of death: ICD-9 — 0382
  • Cause of death: ICD-8 — 0382

2 out of 7 registries used, show all original rules.

965

4. Check minimum number of events

None

965

5. Include endpoints

None

965

6. Filter based on genotype QC (FinnGen only)

920

Control definitions (FinnGen only)

Control exclude ASTHMA_SEPTICHE_PNEUMONIA

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 A40
Name in latin Septic(h)aemia pneumococcica

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14540 6399 8046
Only index persons 12041 5409 6632
Unadjusted period prevalence (%)
Whole population 0.21 0.18 0.22
Only index persons 0.23 0.20 0.25
Median age at first event (years)
Whole population 40.52 39.46 41.06
Only index persons 36.59 36.71 36.49

-FinnGen-

Key figures

All Female Male
Number of individuals 920 407 513
Unadjusted period prevalence (%) 0.24 0.18 0.28
Median age at first event (years) 57.48 51.15 62.50

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: PNEUMO_SEPTHICHE – Pneumococcal septicemia

GWS hits: 1

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