hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.
Pre-eclampsia superimposed on chronic hypertension
DOID EFO Endpoint Browser PheWeb
O15_PREECLAMPS_CHRONIC_HYPERT
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleonly females |
239906 |
2. Check conditionsNone |
239906 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
168 |
4. Check minimum number of eventsNone |
168 |
5. Include endpointsNone |
168 |
6. Filter based on genotype QC (FinnGen only) |
164 |
Control definitions (FinnGen only)
Control exclude
O15_OEDEM_PROTUR_HYPERT
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O10-O16
Name in latin
Hypertensio prae-existens cum proteinuria superposita
Similar endpoints
↥List of similar endpoints to Pre-eclampsia superimposed on chronic hypertension based on the number of shared cases.
Broader endpoints:
- Pre-eclampsia or eclampsia
- Pre-eclampsia or poor fetal growth
- Pregnancy hypertension
- Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
- Delivery, wide proxy
Narrower endpoints:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1336 | 1336 | - |
Only index persons | 1325 | 1325 | - |
Unadjusted period prevalence (%) | |||
Whole population | 0.04 | 0.04 | - |
Only index persons | 0.05 | 0.05 | - |
Median age at first event (years) | |||
Whole population | - | 32.55 | - |
Only index persons | - | 32.55 | - |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 164 | 164 | - |
Unadjusted period prevalence (%) | 0.07 | 0.07 | - |
Median age at first event (years) | 33.18 | 33.18 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: O15_PREECLAMPS_CHRONIC_HYPERT – Pre-eclampsia superimposed on chronic hypertension
GWS hits: -
Loading Relationships table