Placenta praevia

O15_PLAC_PRAEVIA

placenta praevia: Abnormal placentation in which the placenta implants in the lower segment of the uterus (the zone of dilation) and may cover part or all of the opening of the cervix. It is often associated with serious antepartum bleeding and premature labor.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O44
  • Hospital discharge: ICD-9 641[0-1]
  • Cause of death: ICD-10 O44
  • Cause of death: ICD-9 641[0-1]

2 out of 7 registries used, show all original rules.

1454

4. Check minimum number of events

None

1454

5. Include endpoints

None

1454

6. Filter based on genotype QC (FinnGen only)

1400

Control definitions (FinnGen only)

Control exclude O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O30-O48
Name in latin Placenta praevia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13295 13295 -
Only index persons 13162 13162 -
Unadjusted period prevalence (%)
Whole population 0.38 0.38 -
Only index persons 0.48 0.48 -
Median age at first event (years)
Whole population - 32.14 -
Only index persons - 32.12 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1400 1400 -
Unadjusted period prevalence (%) 0.61 0.61 -
Median age at first event (years) 32.13 32.13 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: O15_PLAC_PRAEVIA – Placenta praevia

GWS hits: 3

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