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Premature rupture of membranes

DOID EFO Endpoint Browser PheWeb

O15_MEMBR_PREMAT_RUPT

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O42
  • Hospital discharge: ICD-9 — 6581A
  • Hospital discharge: ICD-8 — 63495
  • Cause of death: ICD-10 — O42
  • Cause of death: ICD-9 — 6581A
  • Cause of death: ICD-8 — 63495

2 out of 7 registries used, show all original rules.

8447

4. Check minimum number of events

None

8447

5. Include endpoints

None

8447

6. Filter based on genotype QC (FinnGen only)

8093

Control definitions (FinnGen only)

Control exclude O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O30-O48
Name in latin Ruptura membranarum fetalium praematura

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 74821 74821 -
Only index persons 74107 74107 -
Unadjusted period prevalence (%)
Whole population 2.14 2.14 -
Only index persons 2.72 2.72 -
Median age at first event (years)
Whole population - 30.02 -
Only index persons - 30.01 -

-FinnGen-

Key figures

All Female Male
Number of individuals 8093 8093 -
Unadjusted period prevalence (%) 3.51 3.51 -
Median age at first event (years) 30.42 30.42 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: O15_MEMBR_PREMAT_RUPT – Premature rupture of membranes

GWS hits: 1

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