Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

O15_EXIST_HYPERT_COMPLIC

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O10
  • Hospital discharge: ICD-9 6420
  • Cause of death: ICD-10 O10
  • Cause of death: ICD-9 6420

2 out of 7 registries used, show all original rules.

2584

4. Check minimum number of events

None

2584

5. Include endpoints

None

2584

6. Filter based on genotype QC (FinnGen only)

2527

Control definitions (FinnGen only)

Control exclude O15_OEDEM_PROTUR_HYPERT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O10-O16
Name in latin Hypertensio prae-existens graviditatem, partum et/sive puerperium complicans

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 20952 20952 -
Only index persons 20618 20618 -
Unadjusted period prevalence (%)
Whole population 0.60 0.60 -
Only index persons 0.76 0.76 -
Median age at first event (years)
Whole population - 32.95 -
Only index persons - 32.90 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2527 2527 -
Unadjusted period prevalence (%) 1.10 1.10 -
Median age at first event (years) 33.03 33.03 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: O15_EXIST_HYPERT_COMPLIC – Pre-existing hypertension complicating pregnancy, childbirth and the puerperium

GWS hits: 3

loading spinner Loading Relationships table