Abnormal findings on antenatal screening of mother

O15_ANTENAT_ABNORM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O28
  • Hospital discharge: ICD-9 7923
  • Cause of death: ICD-10 O28
  • Cause of death: ICD-9 7923

2 out of 7 registries used, show all original rules.

2538

4. Check minimum number of events

None

2538

5. Include endpoints

None

2538

6. Filter based on genotype QC (FinnGen only)

2419

Control definitions (FinnGen only)

Control exclude O15_PREG_OTHER_MAT_DISORD

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O20-O29
Name in latin Abnormitates in examinatione antenatali matris repertae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26387 26387 -
Only index persons 26230 26230 -
Unadjusted period prevalence (%)
Whole population 0.76 0.76 -
Only index persons 0.96 0.96 -
Median age at first event (years)
Whole population - 29.93 -
Only index persons - 29.93 -

-FinnGen-

Key figures

All Female Male
Number of individuals 2419 2419 -
Unadjusted period prevalence (%) 1.05 1.05 -
Median age at first event (years) 30.84 30.84 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: O15_ANTENAT_ABNORM – Abnormal findings on antenatal screening of mother

GWS hits: 3

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