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Other disorders of amniotic fluid and membranes

DOID EFO Endpoint Browser PheWeb

O15_AMNIOT_OTHER

oligohydramnios: A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only females

239906

2. Check conditions

None

239906

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O41
  • Hospital discharge: ICD-9 — 658
  • Hospital discharge: excluded ICD-9 — 6581A
  • Cause of death: ICD-10 — O41
  • Cause of death: ICD-9 — 658
  • Cause of death: excluded ICD-9 — 6581A

2 out of 7 registries used, show all original rules.

4937

4. Check minimum number of events

None

4937

5. Include endpoints

None

4937

6. Filter based on genotype QC (FinnGen only)

4742

Control definitions (FinnGen only)

Control exclude O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3
Parent code in ICD-10 O30-O48
Name in latin Aliae morbositates liquoris amniotici et membranarum fetalium

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 44809 44809 -
Only index persons 44328 44328 -
Unadjusted period prevalence (%)
Whole population 1.28 1.28 -
Only index persons 1.63 1.63 -
Median age at first event (years)
Whole population - 29.82 -
Only index persons - 29.81 -

-FinnGen-

Key figures

All Female Male
Number of individuals 4742 4742 -
Unadjusted period prevalence (%) 2.06 2.06 -
Median age at first event (years) 30.32 30.32 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: O15_AMNIOT_OTHER – Other disorders of amniotic fluid and membranes

GWS hits: 3

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