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Other specified disorders of kidney and ureter

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N14_OTHETNASKIDUR

renal artery obstruction: Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular).

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N28.0, N28.8, N28.9
  • Hospital discharge: ICD-9 — 593[0-1]|5938
  • Hospital discharge: ICD-8 — 59322
  • Hospital discharge: excluded ICD-8 — 5938B
  • Cause of death: ICD-10 — N28.0, N28.8, N28.9
  • Cause of death: ICD-9 — 593[0-1]|5938
  • Cause of death: ICD-8 — 59322
  • Cause of death: excluded ICD-8 — 5938B

2 out of 7 registries used, show all original rules.

977

4. Check minimum number of events

None

977

5. Include endpoints

None

977

6. Filter based on genotype QC (FinnGen only)

948

Control definitions (FinnGen only)

Control exclude N14_KIDUROTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8686 4317 4295
Only index persons 7320 3755 3565
Unadjusted period prevalence (%)
Whole population 0.12 0.12 0.12
Only index persons 0.14 0.14 0.14
Median age at first event (years)
Whole population 54.35 54.58 53.91
Only index persons 51.26 51.89 50.59

-FinnGen-

Key figures

All Female Male
Number of individuals 948 504 444
Unadjusted period prevalence (%) 0.23 0.22 0.24
Median age at first event (years) 53.74 47.81 60.47

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: N14_OTHETNASKIDUR – Other specified disorders of kidney and ureter

GWS hits: -

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