Male infertility

N14_MALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

only males

189303

2. Check conditions

None

189303

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N46
  • Hospital discharge: ICD-9 606
  • Hospital discharge: ICD-8 606
  • Cause of death: ICD-10 N46
  • Cause of death: ICD-9 606
  • Cause of death: ICD-8 606

2 out of 7 registries used, show all original rules.

1531

4. Check minimum number of events

None

1531

5. Include endpoints

None

1531

6. Filter based on genotype QC (FinnGen only)

1429

Control definitions (FinnGen only)

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Infertilitas masculina

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18987 - 18987
Only index persons 18715 - 18715
Unadjusted period prevalence (%)
Whole population 0.53 - 0.53
Only index persons 0.71 - 0.71
Median age at first event (years)
Whole population - - 33.28
Only index persons - - 33.23

-FinnGen-

Key figures

All Female Male
Number of individuals 1429 - 1429
Unadjusted period prevalence (%) 0.79 - 0.79
Median age at first event (years) 33.61 - 33.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: N14_MALEINFERT – Male infertility

GWS hits: 1

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