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Hydronephrosis

DOID EFO Endpoint Browser PheWeb

N14_HYDRONEPHR

hydronephrosis: Collection of urine in the renal pelvis that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N13.0, N13.1, N13.2, N13.3
  • Hospital discharge: ICD-9 — 591
  • Hospital discharge: ICD-8 — 591
  • Cause of death: ICD-10 — N13.0, N13.1, N13.2, N13.3
  • Cause of death: ICD-9 — 591
  • Cause of death: ICD-8 — 591

2 out of 7 registries used, show all original rules.

3683

4. Check minimum number of events

None

3683

5. Include endpoints

None

3683

6. Filter based on genotype QC (FinnGen only)

3542

Control definitions (FinnGen only)

Control exclude N14_RENALTUB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36341 17231 18729
Only index persons 29748 14472 15276
Unadjusted period prevalence (%)
Whole population 0.51 0.49 0.52
Only index persons 0.56 0.53 0.58
Median age at first event (years)
Whole population 64.20 61.27 66.85
Only index persons 62.75 59.10 66.22

-FinnGen-

Key figures

All Female Male
Number of individuals 3542 1677 1865
Unadjusted period prevalence (%) 0.88 0.73 1.03
Median age at first event (years) 62.48 55.74 68.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: N14_HYDRONEPHR – Hydronephrosis

GWS hits: -

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