acute kidney tubular necrosis: Acute renal failure caused by the cell death of the renal tubules. Causes include nephrotoxins, cytotoxic drugs, and antibiotics.
Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
DOID EFO Endpoint Browser PheWeb
N14_DRUGSANDHEAVYMETAL
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
429209 |
1. Apply sex-specific ruleNone |
429209 |
2. Check conditionsNone |
429209 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
86 |
4. Check minimum number of eventsNone |
86 |
5. Include endpointsNone |
86 |
6. Filter based on genotype QC (FinnGen only) |
85 |
Control definitions (FinnGen only)
Control exclude
N14_RENALTUB
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N10-N16
Name in latin
Condiciones tubulo-interstitiales et tubulares ex medicamentis et metallis gravibus
Similar endpoints
↥List of similar endpoints to
Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
based on the number of shared cases.
Broader endpoints:
- Renal tubulo-interstitial diseases
- Genitourinary diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Narrower endpoints:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 684 | 289 | 389 |
| Only index persons | 549 | 241 | 308 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 64.13 | 65.48 | 62.95 |
| Only index persons | 62.02 | 64.29 | 60.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 85 | 35 | 50 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 56.26 | 57.58 | 55.34 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Relationships between endpoints
↥Index endpoint: N14_DRUGSANDHEAVYMETAL – Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
GWS hits: -
Loading Relationships table