Myeloproliferative diseases (CML excluded)

MYELOPROF_NONCML

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

  • not CML
428936

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2099

6. Filter based on genotype QC (FinnGen only)

2043

Control definitions (FinnGen only)

Control conditions not CML

Extra metadata

First used in FinnGen datafreeze DF2, additional

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17116 9105 7806
Only index persons 13283 7288 5995
Unadjusted period prevalence (%)
Whole population 0.24 0.26 0.22
Only index persons 0.25 0.27 0.23
Median age at first event (years)
Whole population 66.96 67.88 65.89
Only index persons 65.96 66.95 64.75

-FinnGen-

Key figures

All Female Male
Number of individuals 2043 1055 988
Unadjusted period prevalence (%) 0.50 0.46 0.54
Median age at first event (years) 63.83 62.64 65.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints

Index endpoint: MYELOPROF_NONCML – Myeloproliferative diseases (CML excluded)

GWS hits: 18

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