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Spondylolisthesis/Spondylolysis

DOID EFO Endpoint Browser PheWeb

M13_SPONDYLOLISTHESIS

spondylolisthesis: A condition in which there is forward displacement of a vertebral bone over the on below it.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M43.0, M43.1
  • Hospital discharge: ICD-9 — 7384
  • Cause of death: ICD-10 — M43.0, M43.1
  • Cause of death: ICD-9 — 7384

2 out of 7 registries used, show all original rules.

6515

4. Check minimum number of events

None

6515

5. Include endpoints

None

6515

6. Filter based on genotype QC (FinnGen only)

6372

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 48651 28486 20045
Only index persons 47184 27814 19370
Unadjusted period prevalence (%)
Whole population 0.71 0.82 0.56
Only index persons 0.91 1.02 0.74
Median age at first event (years)
Whole population 54.63 57.47 50.61
Only index persons 54.46 57.28 50.41

-FinnGen-

Key figures

All Female Male
Number of individuals 6372 4140 2232
Unadjusted period prevalence (%) 1.60 1.80 1.23
Median age at first event (years) 56.74 57.08 56.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_SPONDYLOLISTHESIS – Spondylolisthesis/Spondylolysis

GWS hits: 2

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