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Spinal instabilities

EFO MESH Endpoint Browser PheWeb

M13_SPININSTAB

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

429209

1. Apply sex-specific rule

None

429209

2. Check conditions

None

429209

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M53.2
  • Cause of death: ICD-10 — M53.2

2 out of 7 registries used, show all original rules.

938

4. Check minimum number of events

None

938

5. Include endpoints

None

938

6. Filter based on genotype QC (FinnGen only)

909

Control definitions (FinnGen only)

Control exclude M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M53
Name in latin Instabilitates dorsi

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5536 3333 2184
Only index persons 5425 3281 2144
Unadjusted period prevalence (%)
Whole population 0.08 0.10 0.06
Only index persons 0.11 0.12 0.08
Median age at first event (years)
Whole population 47.96 49.06 46.26
Only index persons 47.85 48.96 46.14

-FinnGen-

Key figures

All Female Male
Number of individuals 909 599 310
Unadjusted period prevalence (%) 0.23 0.26 0.17
Median age at first event (years) 51.24 50.71 52.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Relationships between endpoints

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Index endpoint: M13_SPININSTAB – Spinal instabilities

GWS hits: -

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